HORDB

ID: hor004472
Uniprot ID: P85809
Protein name: Tachykinin-related peptide 8
Gene name: NA
Organism: Rhodnius prolixus (Triatomid bug)
Family: Tachykinin family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Rhodnius (genus), Triatominae (subfamily), Reduviidae (family), Reduvioidea (superfamily), Cimicomorpha (infraorder), Panheteroptera, Neoheteroptera, Euheteroptera, Heteroptera (suborder), Prosorrhyncha, Hemiptera (order), Paraneoptera (cohort), Neoptera (infraclass), Pterygota (subclass), Dicondylia, Insecta (class), Hexapoda (subphylum), Pancrustacea, Mandibulata, Arthropoda (phylum), Panarthropoda, Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Function: Myoactive peptide. Increases the amplitude and frequency of spontaneous contractions and tonus of hindgut muscle.
Mechanism: NA
Cross BBB: NA
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor004472_AF2.pdb

hor004472_ESM.pdb

Mass:	68028	Formula:	C27H44N8O6S
Absent amino acids:	ACDEHIKLNPQSTWY	Common amino acids:	FGMRV
pI:	10.55	Basic residues:	1
Polar residues:	1	Hydrophobic residues:	2
Hydrophobicity:	80	Boman Index:	-461
Half-Life:	1.1 hour	Half-Life Yeast:	3 min
Half-Life E.Coli:	2 min	Aliphatic Index	58
Instability Index:	-2406	Extinction Coefficient cystines:	0
Absorbance 280nm:	0